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| Contemporary Notables of the name Wygle (post 1700) | + |
- Brien Singleton Wygle (1924-2020), American pilot from Seattle, Washington, co-pilot of the first Boeing 747 flight
- Patsy Wygle, American actress, known for When Nature Calls (1985) and Law & Order: Special Victims Unit (1999)
- Kathleen Wygle, American actress, known for Pale Rider (1985)and Dark Horse (1992)
- Rachael Wygle, American model and beauty pageant contestant for Miss Texas USA 2008
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