The Sintzer surname is derived from either the place named Sinz near Saarburg; or Sinne, a common river name in Germany.
The surname Sintzer was first found in Saarburg and the Trier-Saarburg district of the Rhineland-Palatinate. First found on record was a Burkhard der Sintzer in Meßkirch in 1294.
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Some of the first settlers of this family name or some of its variants were: Christian Sinzenig, who was naturalized in Pennsylvania in 1715; Fredrick Sinzel, who arrived in Philadelphia in 1754; Peter Sintz, who was a Hessian mercenary in the American Revolution, who stayed on and was on record in North America in 1777.