First found in the cities of Loop and Loope; it is likely that two separate branches of the families emerged in these two regions. The progenitor of the name is believed to have moved to another region from one of these cities, and was therefore referred to as "Loper." The young Loper family was instrumental during this early period, playing a major role in the development of medieval German society.

Some of the first settlers of this family name or some of its variants were: Joseph Loper, who immigrated to Philadelphia in 1804; Remmer Loop, who emigrated from East Frisia to New York in 1855; John Loepp and Elisabeth Loepp, Mennonites who came to Philadelphia in 1877.

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